Kauvery Hospital Performs Combined MitraClip and Left Atrial Appendage Closure in Single High-Risk Cardiac Procedure
Kauvery Hospital, Alwarpet, performed a combined MitraClip and Left Atrial Appendage Closure procedure on a 79-year-old high-risk patient with severe mitral regurgitation and atrial fibrillation. The minimally invasive intervention was completed in a single session, enabling faster recovery and discharge within 48 hours in stable condition after successful treatment.
The procedure was performed on a 79-year-old patient diagnosed with severe mitral regurgitation caused by a flail anterior mitral leaflet, alongside atrial fibrillation and a previous history of transient stroke. The patient was therefore classified as high risk for both heart failure and recurrent stroke.
Mitral valve regurgitation is a cardiac condition in which the mitral valve fails to close properly, resulting in the backward leakage of blood within the heart. While open-heart surgery remains the standard treatment approach, elderly patients and those with multiple comorbidities are often considered unsuitable for surgical intervention. In such cases, minimally invasive transcatheter procedures such as MitraClip provide an effective alternative by improving valve function without open-heart surgery.
The MitraClip procedure involves the insertion of a small clip via a catheter to approximate the mitral valve leaflets, thereby reducing regurgitation and improving cardiac efficiency.
The patient also presented with atrial fibrillation, an irregular heart rhythm associated with an increased risk of stroke due to clot formation in the left atrial appendage, a small pouch in the heart. To mitigate this risk, Left Atrial Appendage Closure was performed using a specialized occluder device, sealing the appendage to prevent clot formation and reduce long-term stroke risk, often limiting the need for prolonged anticoagulation therapy.
To address both critical conditions simultaneously, the cardiac team at Kauvery Hospital performed a combined intervention involving MitraClip-based mitral valve repair and Left Atrial Appendage Closure during the same access route under a single anesthesia session. This integrated approach reduced procedural exposure, minimized overall treatment burden, and improved clinical efficiency.
Post-procedure, the patient was closely monitored for 24 hours and was discharged within 48 hours in stable condition.
Dr Rajaram Anantharaman, Senior Consultant Interventional Cardiologist, stated that careful patient selection and meticulous procedural planning are essential in such advanced cardiac interventions. He noted that combining MitraClip repair with Left Atrial Appendage Closure requires high precision and coordination, but enables a comprehensive treatment solution in a single session, significantly improving outcomes for high-risk patients while reducing complications.
Dr Aravindan Selvaraj, Co Founder and Executive Director of Kauvery Group of Hospitals, stated that accurate diagnosis and timely intervention remain fundamental in managing complex cardiac conditions. He added that the hospital’s cardiology team continuously integrates advancements in minimally invasive cardiac technologies to deliver safe, precise, and patient-centric care, reflecting a commitment to evidence-based treatment that enhances recovery and quality of life.
The successful execution of this combined cardiac procedure highlights a significant advancement in minimally invasive structural heart interventions, reinforcing the growing role of integrated transcatheter therapies in the treatment of complex, high-risk cardiovascular conditions.

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